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Convalescent Plasma for Coronavirus Disease 2019: Dose is the Key

Jiangquan Yu1, Ruiqiang Zheng1, Haibo Qiu2

  • 1Department of Critical Care Medicine, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China.

Journal of Translational Internal Medicine
|September 9, 2021
PubMed
Abstract

No abstract available in PubMed .

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Renal Failure: Dose Adjustments01:11

Renal Failure: Dose Adjustments

In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
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