Mapping Trends and Hotspots Regarding Clinical Research on COVID-19: A Bibliometric Analysis of Global Research
Related Experiment Video
Updated: Oct 21, 2025

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
Demeng Xia1,2, Renqi Yao3,4, Sheng Wang1
1Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.
Insights
This bibliometric analysis reveals China
Area of Science:
- Bibliometrics
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic has spurred extensive global research.
- A comprehensive bibliometric analysis of COVID-19 clinical research is lacking.
Purpose of the Study:
- To conduct a bibliometric analysis of COVID-19 publications from 2020.
- To identify key research trends, influential publications, and institutions in COVID-19 clinical research.
Main Methods:
- Data extracted from Web of Science (WOS) for January-December 2020.
- Bibliometric analysis performed using VOSviewer and CiteSpace.
- Clinical trial data sourced from clinicaltrials.gov.
Main Results:
- China led in publications, citations, and H-index.
- Journal of Medical Virology published the most articles.
- Huazhong University of Science and Technology and researcher JW Wang were highly productive and cited.
Conclusions:
- Diagnosis, prevention, and prognosis remain key research areas.
- Epidemiology and statistics highlight emerging topics.
- Effective treatment development is the primary focus of ongoing clinical trials.
Abstract:
Purpose: The coronavirus disease 2019 (COVID-19) outbreak, which began in December 2019, has not been completely controlled; therefore, COVID-19 has received much attention from countries around the world. Many related clinical studies, such as clinical trials, have been published, but to the knowledge of the authors, there has been no bibliometric analysis of these publications focusing on clinical research studies on COVID-19. Methods: Global publications on COVID-19 from January 2020 to December 2020 were extracted from the Web of Science (WOS) collection database. The VOSviewer software and CiteSpace were employed to perform a bibliometric study. In addition, we obtained information on relevant clinical trials from the website http://clinicaltrials.gov. Results: China published most of the articles in this field and had the highest number of citations and H-index. The Journal of Medical Virology published most of the articles related to COVID-19. In terms of institutions, Huazhong University of Science and Technology had the most publications, and Wang, JW received the highest number of citations. Conclusion: The diagnosis, prevention, and prognosis of COVID-19 are still the focus of attention at present. The overall analysis of the disease were identified as the emerging topics from the perspectives of epidemiology and statistics. However, finding an effective treatment remains the focus of clinical trials.
Related Concept Videos
Pareto Chart
The Pareto chart is named after the Italian economist Vilfredo Pareto, who described the Pareto...
Single Nucleotide Polymorphisms-SNPs
Steps in Outbreak Investigation
Statistical Methods for Analyzing Epidemiological Data
Bias in Epidemiological Studies
Issues And Trends In Healthcare Delivery System
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...

