Ratiometric fluorescent detection of dipicolinic acid as an anthrax biomarker based on a high-nuclearity Yb18 nanoring
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Updated: Oct 21, 2025

A Simple Fluorescence-based Reporter Assay to Identify Cellular Components Required for Ricin Toxin A Chain RTA Trafficking in Yeast
Published on: December 15, 2017
Yanan Ma1, Xiaoping Yang1, Wenxin Hao1
1College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325035, China. xpyang@wzu.edu.cn.
Abstract:
An 18-metal lanthanide nanoring [Yb18(L1)8(HL2)2(OAc)20(MeOH)8(EtOH)6(H2O)4] (1), which shows a ratiometric fluorescent response to DPA, was constructed through the strategy of using two types of polydentate organic ligands. The addition of DPA increases the visible ligand-centered emission, but decreases the NIR lanthanide luminescence of 1. The limit of luminescent detection of 1 for DPA is 1.5 μM. The high fluorescence sensitivity of 1 to DPA is not affected by the existence of interferents such as aromatic carboxylates and ions.
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