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Updated: Oct 21, 2025

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
[Asymptomatic amoebiasis colitis detected during colonoscopy].
Gitte Nyvang Hartmeyer1, Lene Gaarsmand Christensen, Per Vadgaard Andersen
1gitte.hartmeyer@rsyd.dk.
A colonoscopy revealed a cecal tumor in an asymptomatic man, with biopsies confirming Entamoeba histolytica. Early detection and treatment of E. histolytica are crucial to prevent invasive infections.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Parasitology
Background:
- Colorectal cancer screening can incidentally detect other pathologies.
- Asymptomatic individuals may harbor parasitic infections.
Observation:
- A 61-year-old man with a positive colorectal cancer screening test underwent colonoscopy.
- A cecal tumor was identified, and biopsies revealed Entamoeba histolytica trophozoites in the lamina propria.
Findings:
- Species-specific real-time PCR confirmed Entamoeba histolytica in fecal samples.
- The presence of E. histolytica, even years after exposure, is possible.
Implications:
- Entamoeba histolytica infection requires treatment to prevent invasive disease.
- This case highlights the importance of considering parasitic infections in patients with gastrointestinal findings.
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