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Updated: Oct 21, 2025
Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
Published on: October 28, 2015
A photosensitizer with conformational restriction for enhanced photodynamic therapy
Haiqiao Huang1, Saran Long1,2,3, Daipeng Huang1
1State Key Laboratory of Fine Chemicals, Dalian university of Technology, 2 Linggong Road, Dalian 116024, P. R. China. pengxj@dlut.edu.cn.
Abstract:
A rigid hemicyanine CSZ-J and a flexible molecule ESZ-J were synthesized. In particular, the conformationally restrained CSZ-J had higher fluorescence quantum yields, longer fluorescence lifetimes and higher triplet state quantum yields. CSZ-J could generate highly cytotoxic ROS simultaneously via type I and type II processes. This will contribute to the design and development of new photosensitizers in the future.
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