Biology, technology and a bit of serendipity: an interview with Shiva Malek

Biomarker Analysis from Patients with Metastatic PDAC Treated with TGFβ Antibody NIS793 plus Abraxane + Gemcitabine versus Abraxane + Gemcitabine Alone in a Phase II, Open-Label, Randomized Study.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026

Dynamic transitioning between MAPK-driven and WNT-driven cell states drives intestinal cancer and shapes therapy response.

Nature genetics·2026

RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy.

Cancer discovery·2021

ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma.

Nature·2021

Emerging Trends in Cancer Drug Discovery-From Drugging the "Undruggable" to Overcoming Resistance.

Cancer discovery·2021

Dimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation.

Biochemistry·2020

Pharmacokinetics and efficacy of tank water-administered BRAF-inhibitor dabrafenib in a zebrafish melanoma model.

Disease models & mechanisms·2026

Dysregulated microRNA-mRNA networks in SOD1G93A mouse skeletal muscle reveal metabolic impairments in ALS.

Disease models & mechanisms·2026

A patient-derived missense mouse model of Kabuki syndrome 1.

Disease models & mechanisms·2026

Organoids as brain tumour models: bridging the translational gap.

Disease models & mechanisms·2026

Expanding the scope of Mycobacterium abscessus reference strains to improve pulmonary disease modeling.

Disease models & mechanisms·2026

Characterising skull pathologies in the Sost-deficient mouse for preclinical evaluation of sclerosteosis treatments.

Disease models & mechanisms·2026

Modeling the Variance of Passive SiPMs in the Nonlinear Regime.

Sensors (Basel, Switzerland)·2026

Assessing the Credibility of Quantitative Information: A General Framework.

Annals of biomedical engineering·2026

Simplicial SEIQS epidemic dynamics: Bistability and backward bifurcation under a mean-field approximation.

Chaos (Woodbury, N.Y.)·2026

Hopf bifurcation and stability in a tumor-immune model with discrete and distributed delays.

Mathematical biosciences and engineering : MBE·2026

Quantification of various types of uncertainty in biological computational models using fuzzy mass functions.

Mathematical biosciences and engineering : MBE·2026

Majorana Edge Modes in Isolated Wires.

Physical review letters·2026

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Biology, technology and a bit of serendipity: an interview with Shiva Malek

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Biomarker Analysis from Patients with Metastatic PDAC Treated with TGFβ Antibody NIS793 plus Abraxane + Gemcitabine versus Abraxane + Gemcitabine Alone in a Phase II, Open-Label, Randomized Study.

Dynamic transitioning between MAPK-driven and WNT-driven cell states drives intestinal cancer and shapes therapy response.

RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy.

ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma.

Emerging Trends in Cancer Drug Discovery-From Drugging the "Undruggable" to Overcoming Resistance.

Dimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation.

Pharmacokinetics and efficacy of tank water-administered BRAF-inhibitor dabrafenib in a zebrafish melanoma model.

Dysregulated microRNA-mRNA networks in SOD1G93A mouse skeletal muscle reveal metabolic impairments in ALS.

A patient-derived missense mouse model of Kabuki syndrome 1.

Organoids as brain tumour models: bridging the translational gap.

Expanding the scope of Mycobacterium abscessus reference strains to improve pulmonary disease modeling.

Characterising skull pathologies in the Sost-deficient mouse for preclinical evaluation of sclerosteosis treatments.

Modeling the Variance of Passive SiPMs in the Nonlinear Regime.

Assessing the Credibility of Quantitative Information: A General Framework.

Simplicial SEIQS epidemic dynamics: Bistability and backward bifurcation under a mean-field approximation.

Hopf bifurcation and stability in a tumor-immune model with discrete and distributed delays.

Quantification of various types of uncertainty in biological computational models using fuzzy mass functions.

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Biology, technology and a bit of serendipity: an interview with Shiva Malek

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