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Updated: Oct 21, 2025

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Positive feedback amplification in swarming immune cell populations

Katharina M Glaser1, Michael Mihlan2, Tim Lämmermann2

  • 1Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany; International Max Planck Research School for Immunobiology, Epigenetics and Metabolism (IMPRS-IEM), Freiburg, Germany; Faculty of Biology, University of Freiburg, Freiburg, Germany.

Current Opinion in Cell Biology
|September 9, 2021
PubMed
Summary

Immune cells like neutrophils can swarm, moving collectively through tissues via directed chemotaxis. This coordinated cell migration, driven by intercellular communication and positive feedback, is crucial for immune responses.

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