Related Experiment Video

Updated: Oct 21, 2025

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

486

The Relationship between PI-RADS Categories and Incidental Findings in Multiparametric Prostate MRI

Suna Sahin Ediz1, Nesrin Gunduz2

  • 1Department of Radiology, University of Health Sciences, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|September 10, 2021
PubMed
Abstract

Insights

Extraprostatic incidental findings (ep-IFs) are common during multiparametric prostate MRI (mp-MRI). While benign ep-IFs are frequent, rare malignant findings may be missed, and PI-RADS scores do not aid in their diagnosis.

Area of Science:

  • Radiology and Medical Imaging
  • Oncology
  • Urology

Background:

  • Multiparametric magnetic resonance imaging (mp-MRI) is crucial for prostate cancer detection.
  • Extraprostatic incidental findings (ep-IFs) can occur during prostate mp-MRI.
  • The significance and detection rate of ep-IFs in relation to PI-RADS scores require further investigation.

Purpose of the Study:

  • To determine the frequency and clinical significance of ep-IFs detected during prostate mp-MRI.
  • To compare the incidence of ep-IFs between different PI-RADS score groups.
  • To evaluate the utility of the PI-RADS scoring system in identifying incidental findings.

Main Methods:

  • An analytical study was conducted involving 185 men who underwent prostate mp-MRI.
  • Images were reviewed for ep-IFs, which were classified as urologic/non-urologic and benign/malignant.
  • Patients were categorized into PI-RADS score groups (1-2 vs. 3+), and ep-IFs were compared between groups.

Main Results:

  • A total of 139 ep-IFs were identified in 88 patients (47.6%).
  • The majority of ep-IFs were benign (96.6%), with only 3.4% being malignant.
  • There was no significant difference in the frequency of ep-IFs between PI-RADS score groups (p>0.05).

Conclusions:

  • Ep-IFs are frequently detected during prostate mp-MRI, with benign findings being common.
  • Rare malignant ep-IFs might be overlooked due to the focused interpretation of the prostate.
  • The PI-RADS scoring system does not appear to assist in the diagnosis of incidental mp-MRI findings.

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