Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A microcomputer program for hydropathic analysis of proteins with I/O through word processing and graphics software.

M J Weise1

  • 1Department of Neurology, Medical University of South Carolina, Charleston 29425.

Computer Applications in the Biosciences : CABIOS
|June 1, 1986
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deadly diving? Physiological and behavioural management of decompression stress in diving mammals.

Proceedings. Biological sciences·2011
Same author

Tracking apex marine predator movements in a dynamic ocean.

Nature·2011
Same author

The Neurospora crassa genome: cosmid libraries sorted by chromosome.

Genetics·2001
Same author

The Arabidopsis profilin gene family. Evidence for an ancient split between constitutive and pollen-specific profilin genes.

Plant physiology·1996
Same author

Sequence, function, and phylogenetic analysis of an ascovirus DNA polymerase gene.

Virology·1996
Same author

An approach to searching protein sequences for superfamily relationships or chance similarities relevant to the molecular mimicry hypothesis: application to the basic proteins of myelin.

Journal of neurochemistry·1988

A new BASIC program simplifies protein hydropathic analysis using the Kyte-Doolittle method. It generates editable bar graphs and data tables for enhanced sequence analysis and visualization.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Protein Science

Background:

  • Hydropathic analysis is crucial for understanding protein structure and function.
  • The Kyte-Doolittle method (1982) is a widely used approach for this analysis.
  • Manual analysis can be time-consuming and labor-intensive.

Purpose of the Study:

  • To develop a user-friendly BASIC program for automated hydropathic analysis of protein sequences.
  • To provide researchers with an efficient tool for generating hydropathic profiles.
  • To facilitate the integration of hydropathy data into further computational analyses.

Main Methods:

  • Implementation of the Kyte-Doolittle hydropathic analysis method in a BASIC program.
  • Utilizing input files created with standard word processors.

Related Experiment Videos

  • Generating two output formats: editable bar graphs and tabulated hydropathic indices.

    • Main Results:

    • The program successfully generates visual hydropathic profiles (bar graphs) and numerical data.
    • Output files are compatible with other graphics and analysis software.
    • The system requires only an MS-DOS microcomputer and a dot matrix printer.
    • The program supports unattended analysis of up to 15 input files.

    Conclusions:

    • This BASIC program offers an accessible and efficient solution for protein hydropathic analysis.
    • It simplifies the visualization and data handling of hydropathy profiles.
    • The tool can aid researchers in predicting protein transmembrane regions and other structural features.