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Updated: Aug 4, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
MATCH-UP/MATRIX: a microcomputer program designed to search for protein primary structure homology
1Department of Biological Chemistry, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.
Abstract:
MATCH-UP/MATRIX is a program designed to aid the investigator interested in determining primary protein structure. It is written in Applesoft BASIC for the Apple IIe microcomputer. MATCH-UP will survey any set of proteinaceous materials for amino acid sequence homology; however, it is primarily intended to compare the structures of newly sequenced peptides with the established structure of a protein with suspected homology. Any peptide-to-protein alignment which shows a homology greater than or equal to the percentage specified by the user will result in output. MATRIX will compare the sequences of two proteins (peptides) in whatever alignment specified by the user and is intended to spot insertions and/or deletions between structures.
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