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Postirradiation meningioma.

R Cantini1, M Burchianti, M G Fabrini

  • 1Institute of Neurosurgery, University of Pisa, S. Chiara General Hospital, Italy.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|January 1, 1987
PubMed
Summary
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Radiation therapy for pediatric cerebellar tumors may increase the risk of secondary meningioma. Careful consideration of radiation necessity is crucial, especially in children due to their sensitive meninges.

Area of Science:

  • Neuro-oncology
  • Radiation oncology
  • Pediatric oncology

Background:

  • Meningiomas are primary tumors of the meninges.
  • Radiation therapy is a common treatment for brain tumors, including spongioblastoma.
  • Secondary malignancies can arise years after radiation exposure.

Observation:

  • A case report details a meningioma in the posterior cranial fossa.
  • This tumor developed 12 years after radiation treatment for a cerebellar polar spongioblastoma.
  • The patient was an 8-year-old boy at the time of initial treatment.

Findings:

  • The study discusses the potential role of prior radiation in the development of the secondary meningioma.
  • Post-irradiation tumors, including meningiomas, can exhibit malignancy.

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  • The latency period of 12 years suggests a long-term effect of radiation.
  • Implications:

    • The findings highlight the oncogenic risk associated with radiation therapy in pediatric patients.
    • There is a need for careful evaluation of the necessity of radiation therapy, especially in children.
    • Minimizing radiation exposure in pediatric patients may reduce the risk of secondary tumors like meningioma.