Ocoxin oral solution demonstrates antiviral properties in cellular models.

Area of Science:

• Virology
• Cell Biology
• Nutritional Science

Background:

• Nutritional supplements like Ocoxin Oral Solution (OOS) and Viusid (VS) contain natural products impacting cellular functions.
• Some components of these supplements are known to possess antiviral properties.
• The study explored the potential of OOS and VS in protecting against viral infections.

Purpose of the Study:

• To evaluate the impact of OOS and VS on viral infection.
• To determine if these nutritional supplements can inhibit viral entry or replication.

Main Methods:

• Lentivirus and retrovirus encoding green fluorescent protein were utilized.
• A hemagglutinin-tagged ERK5 was incorporated into the retroviral vector to assess infection.
• HeLa cells were infected with viral particles in the presence or absence of OOS or VS.

Main Results:

• Viusid (VS) demonstrated minimal impact on lentiviral or retroviral infection of HeLa cells.
• Ocoxin Oral Solution (OOS) significantly reduced HeLa cell infection by both viruses.
• The antiviral effect of OOS was dose-dependent, with maximum efficacy observed at a 1:100 dilution.

Conclusions:

• Ocoxin Oral Solution (OOS) exhibits antiviral properties, in addition to its known antitumoral effects.
• OOS may play a role in reducing the severity of viral infections.
• These findings are particularly relevant for cancer patients undergoing oncological therapies, who are more susceptible to viral infections.