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Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer
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The centrifugal viscometer.

Chih-Hsin Shih1, Chia-Chin Chang1, Chung-Yi Liu1

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A new centrifugal viscometer measures low-volume liquid viscosity quickly. This portable device uses disk rotation and deflection angles for accurate, inexpensive viscosity measurements, ideal for various applications.

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Area of Science:

  • Fluid Dynamics
  • Mechanical Engineering
  • Materials Science

Background:

  • Accurate viscosity measurement is crucial in various scientific and industrial fields.
  • Traditional viscometers often require larger sample volumes and longer measurement times.
  • There is a need for portable, cost-effective, and rapid viscosity measurement tools for low-volume liquids.

Purpose of the Study:

  • To develop and validate a novel centrifugal viscometer capable of measuring the viscosity of micro-volume liquid samples.
  • To design a portable and low-cost instrument for rapid viscosity determination.
  • To assess the performance of the developed viscometer against conventional methods.

Main Methods:

  • Development of a centrifugal platform comprising a disk and motor.
  • Utilizing centrifugal, Coriolis, and viscosity-induced drag forces to induce liquid flow deflection.
  • Determining liquid viscosity based on the measured deflection angle of the liquid flow.
  • Image analysis or visual inspection for detecting the deflection angle.
  • Validation using Newtonian model fluids and comparison with a conventional rotational viscometer.

Main Results:

  • The developed centrifugal viscometer successfully measures viscosity of low-volume liquids (25 μl) within 30 seconds.
  • Experimental results showed good agreement between the centrifugal viscometer and a conventional rotational viscometer.
  • The deflection angle of the liquid flow accurately correlates with viscosity.

Conclusions:

  • The centrifugal viscometer offers an inexpensive, easy-to-operate, and portable solution for low-volume liquid viscosity measurement.
  • The microfluidic disk's suitability for mass production via injection molding enhances its cost-effectiveness.
  • This technology has the potential for widespread application in research, quality control, and field testing.