Related Experiment Video
Updated: Oct 20, 2025

Protocol for Isolating the Mouse Circle of Willis
Published on: October 22, 2016
Anatomical Variations in Circle of Willis in Patients Undergoing CT Cerebral Angiography in a Tertiary Hospital in
Prajwal Dhakal1, Prakash Kayastha2, Sharma Paudel2
1Department of Radiology and Imaging, HAMS hospital, Kathmandu, Nepal.
Insights
Anatomical variations in the Circle of Willis are common, affecting over half of patients. Identifying these variations, like a hypoplastic posterior communicating artery, is vital for managing brain vascular pathologies.
Area of Science:
- Neurology
- Radiology
- Vascular Anatomy
Background:
- Variations in the Circle of Willis are frequently observed during computed tomography angiography.
- Accurate identification of these variations is critical for managing cerebrovascular diseases.
- This study focuses on the Nepal population.
Purpose of the Study:
- To determine the prevalence of anatomical variations in the Circle of Willis.
- To investigate the occurrence of aneurysms and other vascular pathologies.
- To assess the utility of CT angiography in detecting these variations.
Main Methods:
- A descriptive cross-sectional study was conducted with 95 patients.
- Convenient sampling was used at Tribhuvan University Teaching Hospital.
- CT angiographic images were analyzed for Circle of Willis variations and vascular pathologies using SPSS.
Main Results:
- Anatomical variations of the Circle of Willis were present in 54.7% of patients.
- The most common variation was a hypoplastic posterior communicating artery (34.7%).
- Aneurysms were identified in 23.2% of the cases.
Conclusions:
- CT angiography is effective for detecting Circle of Willis variations and cerebral aneurysms.
- Recognizing these anatomical variations is crucial for surgical planning and patient management.
- Multidetector CT provides valuable insights into cerebrovascular anatomy.
Introduction:
Variation in Circle of Willis is a commonly encountered entity in patients undergoing computed tomography angiography, identification of which is crucial in the management of patients with vascular pathologies. The aim of the study was to find out the anatomical variations in the Circle of Willis in patients undergoing Computed Tomography cerebral angiography in a tertiary hospital in Nepal.
Methods:
This is a descriptive cross-sectional study involving 95 patients using convenient sampling techniques who were sent to the Department of Radiology and Imaging, Tribhuvan University Teaching hospital, for further evaluation of suspected vascular pathologies in the brain from April 2017 to September 2017. Ethical approval was taken from the Institutional Review Committee of the Institute of Medicine with reference number 326 (6-11-E). CT angiographic images of these patients were evaluated for the presence of variations in Circle of Willis, aneurysms, and other vascular pathologies. Data were analyzed using SPSS.
Results:
Among 95 subjects included in the study, the anatomical variations in the arteries of Circle of Willis was seen in 52 (54.7%) patients, hypoplastic posterior communicating artery being the most common variation 33 (34.7%). The aneurysm was seen in 22 (23.2%) of cases.
Conclusions:
CT Angiography is a commonly performed imaging modality for suspected cases of cerebral aneurysms and various other vascular pathologies. Multidetector computed tomography can effectively detect variations in arteries of Circle of Willis, recognition of which is crucial in operative management of vascular pathologies.
More Related Videos
09:36A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
Published on: August 12, 2025
04:01Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery
Published on: August 9, 2024
Related Concept Videos
Arteries of the Head and Neck
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Imaging Studies for Cardiovascular System V: CT
The Arch of Aorta
Encircling the heart, the coronary arteries form a ring-like structure before...
Aneurysm II: Clinical Manifestations and Diagnostic Studies