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Related Concept Videos

Hypertension I: Introduction01:28

Hypertension I: Introduction

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Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
177
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

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The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
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Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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Hormonal Regulation01:33

Hormonal Regulation

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The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
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Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

3.4K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
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Alterations in Blood Pressure01:30

Alterations in Blood Pressure

1.5K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
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Updated: Oct 20, 2025

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
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Severe hypertension in pregnancy.

Kate Wiles1, Mellisa Damodaram2, Charlotte Frise3

  • 1The Royal London Hospital, London, UK kate.wiles@nhs.net.

Clinical Medicine (London, England)
|September 11, 2021
PubMed
Summary

Severe hypertension in pregnancy requires hospital assessment and prompt blood pressure control, especially with pre-eclampsia, to prevent stroke. Labetalol is commonly used, and this condition increases long-term cardiovascular risk.

Keywords:
hypertensionpre-eclampsiapregnancy

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Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats
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Area of Science:

  • Obstetrics and Gynecology
  • Cardiology
  • Pharmacology

Background:

  • Severe hypertension in pregnancy, defined as systolic BP ≥160 mmHg or diastolic BP ≥110 mmHg, necessitates hospital evaluation.
  • Hypertension before 20 weeks' gestation is uncommon, often linked to chronic hypertension, requiring organ damage assessment and secondary hypertension exclusion.
  • Pre-eclampsia is the leading cause of severe hypertension post-20 weeks' gestation, posing risks like hemorrhagic stroke.

Purpose of the Study:

  • To outline the definition and assessment of severe hypertension in pregnancy.
  • To discuss the common causes and management strategies for severe hypertension during pregnancy.
  • To highlight the association between pregnancy-induced hypertension and long-term maternal cardiovascular health.

Main Methods:

  • Review of diagnostic criteria for severe hypertension in pregnancy.
  • Analysis of common etiologies, including chronic hypertension and pre-eclampsia.
  • Discussion of current treatment approaches and commonly used antihypertensive agents like labetalol.

Main Results:

  • Severe hypertension requires immediate attention due to risks of stroke and other complications.
  • Labetalol is the predominant antihypertensive agent used in the UK for severe hypertension in pregnancy.
  • Pregnancy-related hypertension is a significant risk factor for sustained hypertension and increased cardiovascular risk post-partum.

Conclusions:

  • Prompt and effective management of severe hypertension in pregnancy is crucial for maternal safety.
  • Evidence-based guidelines for pharmacological treatment are limited, relying on clinical experience and drug availability.
  • Severe hypertension during pregnancy signals an increased risk for future cardiovascular disease in women.