Related Experiment Video
Updated: Oct 20, 2025

07:29
Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
11.8K
Temporal bone squamous cell carcinoma: A change in treatment
C Y V Ngu1, M S Mohd Saad2, I P Tang2
1Sarawak General Hospital, Department of Otorhinolaryngology, Malaysia. vincengu1020@gmail.com.
The Medical Journal of Malaysia
|September 11, 2021
Summary
Temporal bone squamous cell carcinoma (TBSCC) is a rare cancer. This case series highlights surgical management challenges and suggests combined surgery and radiotherapy can improve survival for TBSCC patients.
Area of Science:
- Oncology
- Head and Neck Surgery
- Cancer Research
Background:
- Temporal bone squamous cell carcinoma (TBSCC) is a rare malignancy.
- Incidence rates are approximately 0.8-1.0 per million population.
- Management of TBSCC presents significant clinical challenges.
Purpose of the Study:
- To report a case series of surgically managed TBSCC patients.
- To analyze patient presentation and surgical interventions.
- To evaluate short-term survival outcomes.
Main Methods:
- Retrospective case series.
- Inclusion of ten patients undergoing surgery for TBSCC.
- Data collection on patient presentation and surgical procedures.
Main Results:
- Six out of ten patients survived for 2 years post-surgery.
- Surgical intervention was the primary treatment modality.
- Management proved challenging with limited survival data.
Conclusions:
- Adequate surgical resection is crucial for TBSCC management.
- Radiotherapy in conjunction with surgery may enhance patient survival.
- Further research is needed to optimize TBSCC treatment strategies.

