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Study of Febrile Seizure among Hospitalized Children of a Tertiary Centre of Nepal: A Descriptive Cross-sectional

Ram Prasad Pokhrel1, Radha Bhurtel2, Kalpana Karmacharya Malla1

  • 1Department of Paediatrics, College of Medical Sciences Teaching Hospital, Bharatpur, Chitwan, Nepal.

JNMA; Journal of the Nepal Medical Association
|September 11, 2021
PubMed

Insights

Febrile seizures affect 4.37% of hospitalized children in Nepal, with simple febrile seizures being most common. Some children experienced febrile status epilepticus, highlighting the need for awareness.

Area of Science:

  • Pediatrics
  • Neurology
  • Epidemiology

Background:

  • Febrile seizure is the most frequent seizure type in children aged 6-60 months.
  • Understanding its prevalence in specific regions is crucial for public health initiatives.

Purpose of the Study:

  • To determine the prevalence of febrile seizures among hospitalized children in a tertiary care center in Nepal.
  • To identify the types and characteristics of febrile seizures in this population.

Main Methods:

  • A descriptive, cross-sectional study was conducted retrospectively using patient records from January 2014 to December 2019.
  • Data from 4890 admitted children were analyzed, with 214 meeting the criteria for febrile seizure.
  • Statistical analysis included point estimates with 95% Confidence Intervals and frequency calculations.

Main Results:

  • The prevalence of febrile seizure was 4.37% (95% CI: 3.80%-4.94%) among hospitalized children.
  • Simple febrile seizures accounted for 62% of cases.
  • Upper respiratory tract infection was the most common fever cause; 4.6% presented with febrile status epilepticus.

Conclusions:

  • Febrile seizures represent a significant public health concern in hospitalized children in Nepal.
  • Simple febrile seizures are predominant, but a notable proportion experience febrile status epilepticus.
  • Further research into risk factors and management strategies is warranted.
Abstract

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