Related Experiment Video

Updated: Oct 20, 2025

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

812

Pharmacological Treatment for the Management of COVID 19: A Narrative Review

Neelam Dhakal1, Anil Poudyal1, Pradip Gyanwali1

  • 1Nepal Health Research Council, Ramshah Path, Kathmandu, Nepal.

JNMA; Journal of the Nepal Medical Association
|September 11, 2021
PubMed

Insights

This review explores potential treatments for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Nepal. While some antiviral agents show preliminary efficacy, definitive COVID-19 treatment regimens are still under investigation.

Area of Science:

  • Virology
  • Infectious Diseases
  • Pharmacology

Background:

  • The global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a critical public health challenge.
  • Lack of specific vaccines and effective therapeutics necessitates urgent exploration of treatment strategies.
  • The situation in Nepal requires tailored approaches to combatting the SARS-CoV-2 outbreak.

Purpose of the Study:

  • To review potential treatment options for SARS-CoV-2 infections relevant to Nepal's pandemic response.
  • To examine existing antiviral agents and their preliminary efficacy against COVID-19.
  • To identify drugs in clinical trials or with future therapeutic potential for COVID-19.

Main Methods:

  • A comprehensive literature review was conducted.
  • Included 60 relevant articles from the scientific field.
  • Focused on antiviral agents and their mechanisms of action.

Main Results:

  • Preliminary data on the efficacy of some existing antiviral agents were identified.
  • Promising data for an effective COVID-19 treatment regimen are yet to be obtained.
  • Various drugs currently in clinical trials or with potential future use were examined.

Conclusions:

  • The review highlights the ongoing search for effective SARS-CoV-2 treatments.
  • Further research is needed to establish definitive treatment regimens for COVID-19.
  • Understanding drug mechanisms is crucial for future therapeutic development against SARS-CoV-2.

More Related Videos

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-208:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

3.0K
A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects05:46

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

Published on: May 4, 2021

5.3K

Related Concept Videos

Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
508
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
2.8K
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
480
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
264
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
712
Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

Cardiopulmonary Resuscitation IV: Pharmacological Management

Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
126