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Related Experiment Video

Updated: Oct 20, 2025

Metacarpal Small Incision for Carpal Tunnel Syndrome
04:08

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First Carpometacarpal Joint Denervation: A Systematic Review.

Kevin Rezzadeh1, Kristie Rossi2, Corrin C Trerotola2

  • 1Hansjorg Wyss Department of Plastic Surgery, NYU Langone School of Medicine, New York, NY.

The Journal of Hand Surgery
|September 12, 2021
PubMed
Summary

First carpometacarpal (CMC) joint arthritis can be treated with denervation, which shows promise for pain relief and improved hand function. However, results vary, and further research is needed to confirm long-term efficacy.

Keywords:
Arthritisbasilar joint arthritisdenervationfirst carpometacarpal arthritisnerve

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Area of Science:

  • Orthopedic Surgery
  • Hand Surgery
  • Rheumatology

Background:

  • The first carpometacarpal (CMC) joint is a common site for osteoarthritis.
  • Denervation of the first CMC joint is an emerging treatment for CMC arthritis.

Purpose of the Study:

  • To review the existing literature on the denervation of the first CMC joint for treating CMC arthritis.

Main Methods:

  • A systematic review of anatomic and clinical studies was performed, adhering to PRISMA guidelines.
  • Data on patient demographics, surgical techniques, and outcomes were compiled.
  • Anatomical literature was reviewed to understand the joint's innervation.

Main Results:

  • Nine clinical studies and six anatomic studies were included.
  • Patients experienced average improvements in pinch strength, grip strength, and Kapandji scores.
  • Five studies reported pain relief, while common complications included radial paresthesias and wound infections.

Conclusions:

  • First CMC joint denervation shows potential for treating CMC arthritis in the absence of joint instability.
  • Surgical approaches vary due to controversial innervation patterns.
  • Further clinical studies with long-term follow-up and control groups are needed to establish efficacy and longevity.