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Updated: Oct 20, 2025

Novel Sequence Discovery by Subtractive Genomics
Published on: January 25, 2019
Finding unknown species in the genomes of extant species
1State Key Laboratory for Conservation and Utilization of Bio-resource in Yunnan and School of Life Science & School of Ecology and Environmental Science, Yunnan University, Kunming 650091, China.
Abstract:
Although many species have gone extinct, their genetic components might exist in extant species because of ancient hybridization. Via advances in genome sequencing and development of modern population genetics, one can find the legacy of unknown or extinct species in the context of available genomes from extant species. Such discovery can be used as a strategy to search for hidden species or fossils in conservation biology and archeology, gain novel insight into complex evolutionary history, and provide the new sources of genetic variation for breeding and trait improvement in agriculture.
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