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Updated: Oct 20, 2025

Generation of Functional Endodermal Hepatic Organoids
Published on: May 2, 2025
Endo-hepatology: An emerging field
Daniel E Hogan1, Michael Ma2, David Kadosh3
1Division of Gastroenterology, Lenox Hill Hospital, Northwell Health, New York, NY 10075, United States. dhogan3@northwell.edu.
Endoscopic ultrasound (EUS) is revolutionizing liver disease diagnosis and management, offering advanced procedures beyond traditional methods. This technique, termed endo-hepatology, enables precise interventions for various liver conditions.
Area of Science:
- Hepatology
- Gastroenterology
- Medical Imaging
Background:
- Gastroenterologists traditionally manage liver disease using clinical, lab, and imaging data.
- Endoscopic procedures were mainly for esophageal and gastric varices.
- Endoscopic ultrasound (EUS) applications have expanded significantly within hepatology.
Purpose of the Study:
- To highlight the evolving role of EUS in hepatology, a field now termed endo-hepatology.
- To discuss specific EUS-guided diagnostic and therapeutic procedures for liver disease.
Main Methods:
- Review of EUS-guided procedures in liver disease management.
- Discussion of techniques including liver biopsy, shear wave elastography, and portal pressure measurement.
- Exploration of EUS-guided paracentesis and variceal hemorrhage therapy.
Main Results:
- EUS offers a minimally invasive approach to liver disease diagnosis and management.
- Specific EUS procedures provide detailed insights into liver condition and portal hemodynamics.
- EUS facilitates targeted therapies for complications like variceal bleeding.
Conclusions:
- Endo-hepatology, utilizing EUS, represents a significant advancement in liver disease care.
- EUS expands the capabilities of gastroenterologists in managing complex hepatologic conditions.
- This approach enhances diagnostic accuracy and therapeutic efficacy in liver disease patients.
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