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Complete heart block in patients infected with SARS-CoV-2: A case series from a developing country

Muhammad Hammad Sharif1, Abdul Wali Khan2, Madeeha Khaleeque3

  • 1Cardiology Hayatabad Medical Complex, Pakistan.

Annals of Medicine and Surgery (2012)
|September 13, 2021
PubMed

Insights

Coronavirus Disease 19 (COVID-19) can affect the heart's conduction system, causing complete heart block (CHB). This study shows COVID-19 can lead to CHB, which may resolve spontaneously, indicating transient cardiac effects.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Electrophysiology

Background:

  • Coronavirus Disease 19 (COVID-19) is a global pandemic with diverse systemic effects beyond the respiratory system.
  • Emerging evidence suggests cardiovascular complications associated with COVID-19 infection.
  • The impact of COVID-19 on the cardiac conduction system requires further investigation.

Purpose of the Study:

  • To investigate the association between COVID-19 infection and the development of complete heart block (CHB).
  • To present a case series detailing the occurrence of CHB in patients following COVID-19 infection.
  • To contribute to the understanding of cardiovascular outcomes in the context of COVID-19.

Main Methods:

  • Retrospective case series analysis of four patients.
  • Evaluation of cardiac conduction following confirmed COVID-19 infection.
  • Clinical assessment for pre-existing risk factors for complete heart block.

Main Results:

  • Four patients developed new-onset complete heart block (CHB) shortly after COVID-19 infection.
  • These patients had no prior history or risk factors for CHB.
  • The CHB in these cases demonstrated spontaneous recovery, suggesting a transient effect.

Conclusions:

  • COVID-19 infection can adversely affect the cardiac conduction system, leading to CHB.
  • The cardiac effects, specifically CHB, may be transient and reversible following COVID-19.
  • This case series underscores the importance of monitoring cardiac function in COVID-19 patients.

Keywords:
COVID-19Complete heart blockNovel coronavirusSARS-CoV-2

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