Melanosis Peritonei Associated With Adenocarcinoma of the Sigmoid Colon

Area of Science:

• Gastroenterology
• Pathology

Background:

• Melanosis peritonei is a rare condition involving pigment deposition within the peritoneum.
• It is frequently associated with other underlying medical conditions.

Observation:

• During an open repair of a right inguinal hernia in an 86-year-old male patient, extensive black spots were noted on the hernial sac.
• The patient had a history of endoscopic excision of a sigmoid polyp, diagnosed as adenocarcinoma with a narrow surgical margin.

Findings:

• Histopathological and immunohistochemical analyses confirmed the diagnosis of melanosis peritonei.
• The case underscores the rarity of this condition.

Implications:

• Melanosis peritonei must be distinguished from other conditions, particularly metastatic melanoma.
• Accurate diagnosis is crucial for appropriate patient management and prognosis.