End-Stage Tibiotalar Osteoarthritis and Chronic Strontium Toxicity

Area of Science:

• Orthopedics
• Toxicology
• Endocrinology

Background:

• Metal toxicity is a growing concern in orthopedic literature, particularly from implants.
• Strontium toxicity is less understood but can lead to severe systemic effects like osteoporosis.

Observation:

• A 68-year-old female presented with bilateral ankle pain and deformity, diagnosed as osteoarthritis and osteoporosis.
• These conditions were refractory to conservative treatments, including physical therapy and anti-inflammatory medications.

Findings:

• The patient was diagnosed with bilateral osteoarthritis and osteoporosis secondary to strontium toxicity after an extensive workup.
• This is the first reported case linking strontium toxicity to end-stage tibiotalar osteoarthritis.

Implications:

• Clinicians must consider strontium toxicity in patients with unexplained osteoporosis and osteoarthritis.
• A multidisciplinary approach is essential for effective management of strontium toxicity and its orthopedic manifestations.