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Updated: Oct 20, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Young Onset Polyarticular Tophaceous Gout: Rare and Aggressive
Deepshikha Rana1, Zeany C Momin2
1Pathology, University College of Medical Sciences, New Delhi, IND.
Abstract:
Gouty tophi indicate a symptom of chronic gout as a result of an accumulation of monosodium urate crystals in tissues and joints, which is the most predominantly seen form of inflammatory arthritis in the middle-aged and elderly. The rarity with which it is encountered in young adults makes this a formidable diagnostic challenge. In this report, we describe the clinical and cytopathological features of a rare aggressive case of polyarticular tophaceous gout in a young 25-year-old man with atypical involvement of hands, elbow, ankle, and feet to emphasize the importance of considering this disease entity in the differential diagnosis of multiple soft tissue masses in this age bracket as well.
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