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Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles
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Silver nanoparticles in endodontics: recent developments and applications.

Aysenur Oncu1, Yan Huang2, Gulin Amasya3

  • 1Department of Endodontics, Ankara University Faculty of Dentistry, Ankara, Turkey.

Restorative Dentistry & Endodontics
|September 13, 2021
PubMed
Summary

Silver nanoparticles (AgNPs) show significant antimicrobial activity, effectively eliminating endodontic biofilms. This review highlights their properties and potential for successful root canal treatment, improving biomaterial applications in dentistry.

Keywords:
Antimicrobial agentsEndodontic biofilmSilver nanoparticles

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Area of Science:

  • Biomaterials Science
  • Dental Research
  • Nanotechnology in Medicine

Background:

  • Successful root canal treatment relies on eliminating endodontic biofilms and ensuring a leak-proof canal filling.
  • Current biomaterials used in endodontics have limitations affecting treatment success.
  • Silver nanoparticles (AgNPs) are gaining attention for their potent antimicrobial properties in dental applications.

Purpose of the Study:

  • To review the characteristics, limitations, and potential applications of silver nanoparticles (AgNPs) in endodontics.
  • To evaluate the efficacy of AgNPs in eliminating endodontic biofilms.
  • To assess the synthesis, acquisition, usage conditions, and cytotoxicity of AgNPs based on existing clinical studies.

Main Methods:

  • An electronic literature search was performed across major databases: MEDLINE (PubMed), CENTRAL, Google Scholar, and EMBASE.
  • Studies focusing on the application of AgNPs in endodontics were systematically examined.
  • Evaluation of AgNP properties, including chemical, physical, and antimicrobial characteristics, alongside synthesis and cytotoxicity data.

Main Results:

  • Silver nanoparticles exhibit strong antimicrobial activity, making them effective against endodontic biofilms.
  • Various application methods of AgNPs have been investigated in different studies.
  • The synthesis, acquisition methods, usage conditions, and potential cytotoxicity of AgNPs were evaluated.

Conclusions:

  • Silver nanoparticles are highly effective antimicrobial agents for the elimination of endodontic biofilms.
  • AgNPs present a promising biomaterial for enhancing the success of root canal treatments.
  • Further research into AgNP properties and applications may lead to improved endodontic therapies.