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Related Experiment Video

Updated: Oct 20, 2025

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
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Deep Neck Infections: Decisional Algorithm for Patients with Multiple Spaces Involvement.

Filippo Ricciardiello1, Salvatore Mazzone1, Pasquale Viola2

  • 1Ear Nose and Throat Unit, AORN Cardarelli Hospital, Napoli, Italy.

Reviews on Recent Clinical Trials
|September 13, 2021
PubMed
Summary
This summary is machine-generated.

Deep neck infections (DNIs) can lead to life-threatening complications. Identifying predisposing factors like multiple space involvement and comorbidities is crucial for timely surgical intervention and improved patient outcomes.

Keywords:
Deep neck infectionsfascial planesinfection complicationsneck surgerypolymicrobial infectionstherapeutic algorithm

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Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Surgical Pathology

Background:

  • Deep neck infections (DNIs) spread through fascial planes and neck spaces.
  • While antibiotics have reduced incidence, complications remain life-threatening.

Purpose of the Study:

  • Identify predisposing factors for deep neck infection complications.
  • Develop a reliable therapeutic algorithm for managing DNIs.

Main Methods:

  • Retrospective study of 60 patients with DNIs from 2006-2019.
  • Exclusion criteria: cellulitis, small abscesses, single space involvement.
  • Evaluated parameters: demographics, comorbidities, clinical features, bacteriology, surgical approach, complications, outcomes.

Main Results:

  • Comorbidities (Diabetes Mellitus, COPD, anemia) and multiple space involvement significantly increased complication risk.
  • Most infections were polymicrobial; all patients required surgical drainage.
  • Complication rate was 56.6%, with an 18.3% mortality rate.

Conclusions:

  • Deep neck infections are a medical and surgical emergency requiring prompt diagnosis and intervention.
  • Evaluating infection extent is vital; multiple space involvement necessitates timely surgery due to higher complication and mortality risks.