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Updated: Oct 20, 2025

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Biomarker-Based Management of AKI: Fact or Fantasy?
Marlies Ostermann1, Emma Karsten2, Nuttha Lumlertgul1,3,4
1Department of Critical Care, King's College London, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Abstract:
New biomarkers for acute kidney injury (AKI) have improved our understanding of the etiology and pathogenesis of AKI. Depending on their origin, function, and kinetic profile, biomarkers have a role in screening, diagnosis, prognostication, and monitoring of AKI. This offers opportunities to improve the management of AKI, but concerns and limitations remain. In this review, we summarize the current role of new AKI biomarkers in the management of AKI and outline some of the ongoing limitations and challenges.
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