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Related Concept Videos

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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The Porto European Cancer Research Summit 2021.

Ulrik Ringborg1,2, Anton Berns2,3, Julio E Celis2,4

  • 1Cancer Center Karolinska, Karolinska University Hospital, Stockholm, Sweden.

Molecular Oncology
|September 13, 2021
PubMed
Summary
This summary is machine-generated.

European Cancer Mission and Europe's Beating Cancer Plan require networked infrastructures, including Comprehensive Cancer Centres, to advance cancer research and care across the EU. The Porto Declaration calls for collective action to reduce cancer incidence and improve patient outcomes.

Keywords:
Cancer Missioncancer research/care/prevention continuumclinical/prevention trialscomprehensive cancer centresinfrastructures for translational cancer researchoutcomes researchscience policy

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Area of Science:

  • Oncology
  • Public Health Policy
  • Cancer Research Infrastructure

Background:

  • Key stakeholders convened at the European Cancer Research Summit in May 2021.
  • Discussions focused on implementing the European Cancer Mission and Europe's Beating Cancer Plan (EBCP).
  • A consensus emerged on the necessity of robust, networked infrastructures to address cancer challenges.

Purpose of the Study:

  • To outline priorities and action points for cancer research and care implementation in the EU.
  • To define the essential components of European cancer research infrastructures.
  • To foster innovation and reduce inequalities in cancer research and treatment.

Main Methods:

  • The Summit brought together stakeholders from the cancer research continuum.
  • Presentations and discussions focused on three key pillars: translational research, clinical/prevention trials, and outcomes research.
  • The Porto Declaration was presented, outlining a call to action.

Main Results:

  • The need for high-quality, networked infrastructures, with Comprehensive Cancer Centres (CCCs) as central elements, was emphasized.
  • Specific advancements in translational research (multiomics, digital pathology, liquid biopsy) and requirements for next-generation trials were discussed.
  • The importance of outcomes research covering prevention, early detection, and survivorship was highlighted.

Conclusions:

  • The development of integrated cancer research infrastructures is crucial for personalized medicine and reducing cancer burden in Europe.
  • The Porto Declaration signifies a commitment to collective action for cancer research infrastructure development.
  • Successful implementation of EU-wide cancer initiatives can decrease mortality and improve quality of life affordably.