Related Experiment Video For Advanced virtual monoenergetic image
Updated: Oct 20, 2025

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
Published on: December 2, 2013
Usefulness of advanced monoenergetic reconstruction technique in dual-energy computed tomography for detecting
Motoo Nakagawa1, Taku Naiki2, Aya Naiki-Ito3
1Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Japan. motoo@med.nagoya-cu.ac.jp.
Purpose:
Detecting bladder cancer (BC) in routine CT images is important but is sometimes difficult when cancer is small. We evaluated the ability of 40-keV advanced monoenergetic images to depict BC.
Materials And Methods:
Fifty-two patients with a median age of 74 years (range 45-92) who were diagnosed as BC with transurethral resection or cystectomy, were included. They were examined with contrast-enhanced dual-energy CT (DE-CT) and advanced virtual monoenergetic images (40 keV) were reconstructed. For evaluating depictability of BC on 40-keV or virtual-120-kVp images, the difference in CT number between the cancer and bladder wall (BC-BW value) were calculated. We also subjectively assessed depictability of BC in virtual-120-kVp and 40-keV images using a 4-grade Likert scale (3: clear, 0: not visualized).
Results:
In 42 of 52 patients, BC-BW values could be calculated because BC was detected on CT images. The mean BC-BW value at 40 keV was significantly higher than that of virtual 120 kVp [80.5 ± 54 (SD) vs. 11.4 ± 12.5 HU, P < 0.01]. Average scores of subjective evaluations in the virtual-120-kVp and 40-keV images were 1.7 ± 1.2 and 2.1 ± 1.2, respectively (P < 0.001).
Conclusion:
The advanced monoenergetic reconstruction technique reconstructed using DE-CT image is useful to depict BC.
Related Concept Videos
Imaging Studies III: Computed Tomography
Imaging Studies II: Ultrasonography
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Ultrasonography
During an ultrasonography procedure, a handheld device called...
Imaging Studies IV: Magnetic Resonance Imaging
Imaging Studies I: Kidney, Ureter, and Bladder Studies

