Malakoplakia and xanthogranulomatous pyelonephritis treated with nephrectomy: A case report
Yueh Pan1,2,3, Ying Chui Hong4, Hung-Jen Shih1
1Division of Urology, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Medicine
|September 13, 2021
Summary
Malakoplakia and xanthogranulomatous pyelonephritis can occur together. A patient with these simultaneous kidney conditions successfully recovered after a nephrectomy, resolving urosepsis.
Area of Science:
- Nephrology
- Pathology
- Inflammatory Diseases
Background:
- Malakoplakia and xanthogranulomatous pyelonephritis are rare chronic kidney inflammatory conditions.
- These conditions involve significant infiltration of inflammatory cells within the renal tissue.
Observation:
- An 82-year-old female with multiple comorbidities presented with recurrent urosepsis.
- Imaging revealed an enlarged right kidney with a ureteral lesion, initially suspected as xanthogranulomatous inflammation.
Findings:
- Pathology confirmed simultaneous malakoplakia and xanthogranulomatous pyelonephritis in the kidney and ureter.
- Surgical intervention (radical nephrectomy) was performed.
Implications:
- This case highlights that malakoplakia and xanthogranulomatous pyelonephritis are not mutually exclusive.
- Simultaneous occurrence necessitates comprehensive diagnostic and therapeutic approaches for effective management.
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