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Platelets amplify endotheliopathy in COVID-19

Tessa J Barrett1, MacIntosh Cornwell1,2, Khrystyna Myndzar1

  • 1Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA.

Science Advances
|September 13, 2021
PubMed
Summary

COVID-19 platelets release myeloid-related protein (MRP) 8/14, activating endothelial cells and promoting inflammation and hypercoagulability. Targeting platelet P2Y12 may reduce these harmful interactions in COVID-19 patients.

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