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Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

Depressive subfactors and cognitive function in midlife.

Yu Jin Lee¹, Hyeon Chang Kim², Sun Jae Jung³

¹Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea.

Journal of Affective Disorders

|September 13, 2021

Summary

This summary is machine-generated.

The somatic subtype of depression is linked to cognitive decline in midlife adults, particularly in older women. Understanding these depressive subtypes is key to addressing cognitive function differences.

Keywords:

Cognitive function Depressive symptoms Factor analysis Midlife

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Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Area of Science:

Neuroscience
Psychiatry
Gerontology

Background:

Depression presents with heterogeneous subtypes, potentially impacting cognitive function differently.
Midlife adults are a critical demographic for studying the long-term effects of mental health on cognition.

Purpose of the Study:

To investigate the varied associations between depressive subtypes and cognitive function.
To explore how age and sex modify the relationship between depression subtypes and cognition.

Main Methods:

Cross-sectional analysis of 5271 midlife participants from the Cardiovascular and Metabolic Disease Etiology Research Center cohort.
Factor analysis of Beck Depression Inventory II items identified melancholic and somatic depressive subtypes.
Multiple regression analysis adjusted for covariates assessed the association between depressive subtypes and Mini-Mental State Examination scores.

Main Results:

Heterogeneous associations between depressive subtypes and cognitive dysfunction were observed in midlife.
The somatic depressive subtype showed a significant association with cognitive dysfunction.
Older women (over 60) exhibited decreased Mini-Mental State Examination scores with increasing somatic depression scores.

Conclusions:

The somatic subtype of depression appears more strongly associated with cognitive impairment in midlife, especially in older women.
Characterizing depressive subtypes by sex and age is crucial for understanding cognitive dysfunction.
Further validation and reliability testing of depressive subtypes are warranted.