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Updated: Oct 20, 2025
Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
Published on: April 11, 2018
Fully automated noncoplanar radiation therapy treatment planning
Charles Huang1, Yong Yang2, Lei Xing2
1Department of Bioengineering, Stanford University, Stanford, California, USA.
Purpose:
To perform fully automated noncoplanar (NC) treatment planning, we propose a method called NC-POPS to produce NC plans using the Pareto optimal projection search (POPS) algorithm.
Methods:
NC radiation therapy treatment planning has the potential to improve dosimetric quality as compared to traditional coplanar techniques. Likewise, automated treatment planning algorithms can reduce a planner's active treatment planning time and remove inter-planner variability. Our NC-POPS algorithm extends the original POPS algorithm to the NC setting with potential applications to both intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT). The proposed algorithm consists of two main parts: (1) NC beam angle optimization (BAO) and (2) fully automated inverse planning using the POPS algorithm.
Results:
We evaluate the performance of NC-POPS by comparing between various NC and coplanar configurations. To evaluate plan quality, we compute the homogeneity index (HI), conformity index (CI), and dose-volume histogram statistics for various organs-at-risk (OARs). As compared to the evaluated coplanar baseline methods, the proposed NC-POPS method achieves significantly better OAR sparing, comparable or better dose conformity, and similar dose homogeneity.
Conclusions:
Our proposed NC-POPS algorithm provides a modular approach for fully automated treatment planning of NC IMRT cases with the potential to substantially improve treatment planning workflow and plan quality.
