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Clinical, functional and inflammatory evaluation in asthmatic patients after a simple short-term educational program:
Soraia Nogueira Felix1, Rosana Câmara Agondi2, Marcelo Vivolo Aun2
1Instituto de Assistência Médica Ao Servidor Público Estadual (IAMSPE), Sao Paulo, SP, Brazil. soraia.ank@gmail.com.
Scientific Reports
|September 15, 2021
Summary
An educational intervention improved asthma control by reducing inflammation and enhancing lung function. Asthmatic patients experienced better quality of life and reduced depression levels following the program.
Area of Science:
- Pulmonology
- Clinical Medicine
- Health Education
Background:
- Asthma management requires continuous patient engagement.
- Partly controlled and uncontrolled asthma significantly impacts quality of life.
- Inflammatory markers and lung function are key indicators of asthma control.
Purpose of the Study:
- To assess the impact of a nurse-led educational intervention on asthma control.
- To evaluate changes in clinical, functional, and inflammatory parameters in asthmatic patients.
- To determine the effect of education on quality of life and depression in asthma.
Main Methods:
- Randomized controlled trial with 58 adult asthma patients (intervention vs. control group).
- 12-week evaluation period including spirometry, exhaled nitric oxide (NO), breath condensate (EBC), induced sputum (IS), and validated questionnaires (ACT, ACQ, AQLQ, BDI).
- Intervention group received a 30-minute educational session.
Main Results:
- Intervention group showed reduced eosinophils in IS and IL-17A in EBC.
- Significant increase in FEV1 (forced expiratory volume in 1 second) post-bronchodilator in the intervention group.
- Improved quality of life and reduced depression scores observed in the intervention group compared to the control group.
Conclusions:
- Educational interventions are effective in improving asthma control.
- Asthma education can lead to reduced airway inflammation and improved lung function.
- Patient education positively influences quality of life and mental well-being in asthma patients.
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