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Conjunctival Pyogenic Granuloma Masquerading as Malignant Melanoma
Priyanka R Rao1, Amjad U Furniturewala2, Indumati Gopinathan3
1Ophthalmology, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, IND.
Cureus
|September 15, 2021
Summary
Necrotic pyogenic granulomas can mimic conjunctival melanomas. This case highlights the importance of considering benign, albeit rare, presentations that resemble malignant tumors, emphasizing thorough histopathological examination for accurate diagnosis.
Area of Science:
- Ophthalmology
- Dermatopathology
Background:
- Pyogenic granuloma, also known as lobular capillary hemangioma, is a benign vascular proliferation.
- Conjunctival pyogenic granulomas commonly arise after ocular trauma, chalazion, or prosthesis use.
Observation:
- A 44-year-old woman presented with a rapidly enlarging, pedunculated, black conjunctival mass.
- The lesion's appearance raised suspicion for a melanocytic tumor, prompting surgical excision.
Findings:
- Histopathology and immunohistochemistry confirmed the mass as a necrotic pyogenic granuloma.
- The necrotic changes caused the benign lesion to clinically resemble a malignant melanoma.
Implications:
- This case underscores the need for high suspicion with rapidly enlarging pigmented conjunctival lesions.
- Necrotic pyogenic granulomas can present atypically, mimicking conjunctival melanoma and necessitating careful differential diagnosis.
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