Related Experiment Video
Updated: Oct 20, 2025
07:44
Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
10.3K
Clinical Detection of Primary Pulmonary Angiosarcoma
Kaynat Khalid1, Anas Khan1, Christine M Lomiguen2,3
1Department of Primary Care, Lake Erie College of Osteopathic Medicine, Erie, USA.
Cureus
|September 15, 2021
Summary
Pulmonary angiosarcoma (PAS) is a rare vascular tumor. Early detection is crucial, as diagnosis is often delayed, impacting patient prognosis and survival rates.
Area of Science:
- Oncology
- Pathology
- Vascular Biology
Background:
- Pulmonary angiosarcoma (PAS) is a rare, aggressive malignant vascular tumor.
- Late diagnosis is common due to its metastatic nature, leading to poor prognosis.
Observation:
- A 53-year-old male presented with dyspnea and syncope.
- Initial workup revealed bilateral pulmonary embolisms, attributed to atrial fibrillation.
- Subsequent investigations and biopsy confirmed spindle cell pulmonary angiosarcoma.
Findings:
- The time from symptom onset to diagnosis for PAS ranges from 2 to 6 months.
- Median survival is 7 months for solitary lesions and 2 months for multiple lesions at diagnosis.
Implications:
- This case highlights the diagnostic challenges and aggressive nature of PAS.
- Developing screening and detection criteria for earlier diagnosis is suggested.
- Earlier detection and treatment are critical for improving patient outcomes in rare vascular tumors.
