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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Wrist abscess due to drug-resistant Pasteurella multocida
Abraham Wei1, Nehal Dhaduk2, Basil Taha1
1Rutgers New Jersey Medical School, Division of Infectious Diseases, Newark, NJ 07101, USA.
Abstract:
Many cases of cat and dog bites are associated with Pasteurella spp. infections. Antimicrobial therapy usually entails a β-lactam-β-lactamase inhibitor combination such as amoxicillin-clavulanic acid. Drug resistance in human Pasteurella spp. infections has rarely been reported in literature. In this report, we introduce the first documented case of a human Pasteurella spp. infection with resistance to amoxicillin-clavulanic acid. The potential emergence of drug-resistant Pasteurella spp may alter our therapeutic approach to animal bites in the future. This case highlights the need for further epidemiologic studies on Pasteurella spp antibiotic susceptibility patterns in both humans and cats.
Insights
A rare case of Pasteurella spp. infection resistant to amoxicillin-clavulanic acid in a human is reported. This finding highlights the potential emergence of drug-resistant Pasteurella, impacting future animal bite treatment strategies.
Area of Science:
- Infectious Diseases
- Microbiology
- Antimicrobial Resistance
Background:
- Cat and dog bites frequently lead to Pasteurella spp. infections.
- Amoxicillin-clavulanic acid is a common antimicrobial treatment for these infections.
Observation:
- This report details the first documented human Pasteurella spp. infection exhibiting resistance to amoxicillin-clavulanic acid.
- The infection was associated with a cat bite.
Findings:
- The isolated Pasteurella spp. demonstrated resistance to amoxicillin-clavulanic acid.
- This is the first reported instance of such resistance in human Pasteurella infections.
Implications:
- The emergence of drug-resistant Pasteurella spp. may necessitate changes in the therapeutic approach for animal bite-related infections.
- Further epidemiological studies are crucial to understand Pasteurella spp. antibiotic susceptibility patterns in humans and cats.
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