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Updated: Oct 20, 2025

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Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
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Does deep brain stimulation improve Parkinson's disease-related lower urinary tract symptoms and voiding dysfunction?
Alexandra L Tabakin1, Hari S G R Tunuguntla1
1Division of Urology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
Bladder (San Francisco, Calif.)
|September 15, 2021
Summary
Deep brain stimulation (DBS) may help manage lower urinary tract symptoms (LUTS) in Parkinson's disease (PD) patients. This review explores DBS's potential to improve voiding dysfunction and quality of life for those with PD.
Area of Science:
- Neurology
- Urology
- Neurosurgery
Background:
- Parkinson's disease (PD) involves neurodegeneration, causing motor and autonomic issues.
- Lower urinary tract symptoms (LUTS) and voiding dysfunction significantly impact PD patients' quality of life.
- Deep brain stimulation (DBS) is an established therapy for Parkinsonian motor symptoms.
Purpose of the Study:
- To review the current literature on the effects of DBS on lower urinary tract function in PD.
- To evaluate DBS's potential as a treatment for PD-related LUTS and voiding dysfunction.
Main Methods:
- Literature review of studies investigating DBS and urinary function in Parkinson's disease patients.
- Analysis of existing research on the modulation of autonomic and urinary pathways by DBS.
Main Results:
- Evidence suggests DBS may influence lower urinary tract function in Parkinson's disease.
- Further research is needed to establish DBS as a standard treatment for PD-related LUTS.
Conclusions:
- DBS is being explored as a novel therapeutic approach for managing LUTS in Parkinson's disease.
- The efficacy of DBS in modulating PD-related voiding dysfunction warrants further investigation.
Keywords:
Parkinson’s diseasedeep brain stimulationlower urinary tract symptomsneuromodulationvoiding dysfunction
