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Updated: Oct 20, 2025

Author Spotlight: Unraveling the Impact of Mechanical Ventilation on Diaphragm Function and Patient Outcomes
Published on: November 3, 2023
Functional evaluation of the diaphragm with a noninvasive test
Bruno Bordoni1, Allan R Escher2
1Foundation Don Carlo Gnocchi IRCCS, Department of Cardiology, Institute of Hospitalization and Care with Scientific, Milan, Italy.
Cardiac surgery and myocardial infarction can impair diaphragm function, affecting recovery. This review explores diaphragm neurophysiology and dysfunction, proposing a new non-instrumental diagnostic test.
Area of Science:
- Cardiology
- Respiratory Physiology
- Neuromuscular Function
Background:
- Median sternotomy in cardiac surgery causes temporary and permanent diaphragm damage.
- Myocardial infarction induces genetic changes in the diaphragm, leading to maladaptation.
- Diaphragm function is crucial for physical/mental health and post-cardiac event recovery.
Purpose of the Study:
- To review the neurophysiological relationships of the diaphragm.
- To describe symptoms of diaphragmatic contractile dysfunction.
- To propose and provide a scientific basis for a novel non-instrumental diaphragmatic test.
Main Methods:
- Literature review of diaphragm neurophysiology and dysfunction.
- Analysis of existing diagnostic tools (ultrasound, MRI, CT).
- Conceptualization of a new non-instrumental assessment method.
Main Results:
- Established link between cardiac events/surgery and diaphragm dysfunction.
- Detailed review of diaphragmatic contractile dysfunction symptoms.
- Proposed a novel, non-instrumental approach for diaphragm assessment.
Conclusions:
- Diaphragm evaluation is essential in cardiac patient care.
- Current instrumental methods have limitations.
- A new non-instrumental test warrants further research for improved diaphragm assessment.
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