Related Experiment Video
Updated: Oct 20, 2025
14:49
Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Published on: September 29, 2018
42.2K
[An adolescent presenting with knee pain]
J M J Goetstouwers1,2, Maaike P J Van den Borne1, Christiaan J A Van Bergen1
1Amphia ziekenhuis, afd. Orthopedie, Breda.
Nederlands Tijdschrift Voor Geneeskunde
|September 15, 2021
Summary
A 14-year-old experienced persistent knee pain. Doctors diagnosed focal pigmented villonodular synovitis after MRI and arthroscopic surgery confirmed the soft-tissue lesion.
Area of Science:
- Orthopedic Surgery
- Musculoskeletal Pathology
Background:
- Pigmented villonodular synovitis (PVNS) is a rare, benign joint disorder.
- It typically affects young adults and can cause chronic joint pain and swelling.
- Idiopathic causes are common, presenting diagnostic challenges.
Purpose of the Study:
- To report a case of focal pigmented villonodular synovitis in an adolescent.
- To highlight the diagnostic process and successful treatment of this rare condition.
Main Methods:
- A 14-year-old male presented with a two-year history of left knee pain.
- Magnetic Resonance Imaging (MRI) revealed a characteristic soft-tissue lesion.
- Arthroscopic surgical excision of the lesion was performed.
Main Results:
- Pathological examination confirmed the diagnosis of focal pigmented villonodular synovitis.
- The lesion was successfully removed via arthroscopy.
Conclusions:
- Focal pigmented villonodular synovitis can occur in adolescents and present with chronic knee pain.
- Early diagnosis through imaging and confirmation via pathology is crucial for effective management.
Related Concept Videos
01:16Bones of the Lower Limb: Femur and Patella
3.9K
The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the...
3.9K
01:23Knee Joint
2.6K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
2.6K
01:22Appendicitis-I: Introduction
820
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
820
01:23Muscles that Move the Leg
3.6K
The movement of the legs is facilitated by numerous muscles located within the anterior, medial, and posterior compartments of the thigh.
Anterior Compartment
The quadriceps femoris, the most visible muscle of the anterior compartment, is integral for leg extension and thigh flexion. It is formed by merging four distinct muscles — the vastus lateralis, vastus medialis, vastus intermedius, and rectus femoris. The quadriceps tendon, a shared tendon of the four quadriceps muscles, is affixed...
Anterior Compartment
The quadriceps femoris, the most visible muscle of the anterior compartment, is integral for leg extension and thigh flexion. It is formed by merging four distinct muscles — the vastus lateralis, vastus medialis, vastus intermedius, and rectus femoris. The quadriceps tendon, a shared tendon of the four quadriceps muscles, is affixed...
3.6K
01:10Ankle Joint
2.1K
The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
2.1K
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
70
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
70