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One year in review 2021: Behçet's syndrome
Gülen Hatemi1, Emire Seyahi1, Izzet Fresko1
1Division of Rheumatology, Department of Internal Medicine, and Behçet's Disease Research Centre, Istanbul University-Cerrahpasa, School of Medicine, Istanbul, Turkey.
Abstract:
This review aims to provide a critical digest of the recent studies that enhance our understanding of Behçet's syndrome by evaluating time trends, differences in disease course between men and women, and between patients with an early and late disease onset, progress in disease assessment, novel findings on immunopathogenesis and genetics, clinical features and differential diagnosis of eye, vascular, nervous system and gastrointestinal system involvement, and new data on treatment modalities including TNF-alpha, IL-17 and IL-6 inhibitors, tofacitinib, and apremilast, as well as surgical interventions.
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