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    A novel adaptive weighting method, DASDSF, enhances photoacoustic imaging (PAI) by reducing side lobes and noise. This method improves image contrast and signal-to-noise ratio, enabling cost-effective PAI systems with fewer elements.

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    Area of Science:

    • Biomedical Optics
    • Acoustic Imaging
    • Image Reconstruction

    Background:

    • Minimum Variance (MV) beamforming improves spatial resolution in photoacoustic imaging (PAI) by narrowing main lobes.
    • However, MV beamformers suffer from strong side-lobe signals, degrading reconstructed image contrast.
    • Existing methods struggle to effectively suppress these side lobes without compromising image quality.

    Purpose of the Study:

    • To introduce a new adaptive weighting method, delay-and-sum-to-delay-standard-deviation factor (DASDSF), for PAI.
    • To address the side-lobe signal issue in MV beamforming.
    • To enhance image quality, signal-to-noise ratio (SNR), and enable cost-effective PAI systems.

    Main Methods:

    • Developed and integrated the DASDSF adaptive weighting method with MV beamforming.
    • Evaluated the method using numerical simulations and experimental data from a home-built PAI system.
    • Employed a low-cost, 16-element linear transducer array for validation.

    Main Results:

    • The DASDSF method significantly reduced side-lobe signal strength and improved image contrast compared to MV and MV-coherence factor beamformers.
    • Achieved a notable improvement in SNR and a reduction in full-width at half-maximum (FWHM) of the main lobe.
    • Demonstrated robustness against noise reduction.

    Conclusions:

    • The DASDSF weighting approach effectively mitigates side-lobe artifacts in PAI.
    • The proposed method offers superior performance in SNR improvement, spatial resolution, and contrast enhancement.
    • This technique holds promise for developing cost-effective PAI systems utilizing low-cost transducer arrays (e.g., 16 elements).