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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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Thyroid Hemiagenesis Accompanying an Ectopic Lingual Thyroid.

Kai-Fen Chuang1, Jih-Chin Lee1, Che-Jui Lee1

  • 1Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei.

Ear, Nose, & Throat Journal
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PubMed
Summary

This study reports a rare case of ectopic lingual thyroid combined with thyroid hemiagenesis. The patient remained euthyroid but experienced localized symptoms, highlighting a unique clinical presentation.

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Area of Science:

  • Endocrinology
  • Anatomy
  • Medical Case Reports

Background:

  • Thyroid hemiagenesis is a rare congenital anomaly, often asymptomatic and incidentally discovered.
  • Ectopic thyroid tissue, particularly lingual thyroid, is also uncommon.
  • The co-occurrence of these two conditions is exceptionally rare in medical literature.

Observation:

  • A case of thyroid hemiagenesis was identified.
  • An ectopic lingual thyroid was concurrently diagnosed in the same patient.
  • The patient presented with symptoms related to the localized ectopic thyroid tissue.

Findings:

  • The patient was euthyroid, indicating normal thyroid function despite the anatomical abnormalities.
  • The co-existence of thyroid hemiagenesis and ectopic lingual thyroid was confirmed.
  • Regional symptoms were attributed to the presence of the lingual thyroid.

Implications:

  • This case expands the understanding of rare thyroid developmental anomalies.
  • It highlights the importance of considering ectopic thyroid tissue in patients with hemiagenesis, even if asymptomatic.
  • Further research may elucidate the embryological basis for such combined presentations and their clinical management.