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The Emerging Uncommon Non-Albicans Candida: Candida Parapsilosis Peritonitis in a Peritoneal Dialysis Patient

Sasmit Roy1,2, Praveena Vantipalli3, Amarinder Garcha4

  • 1Nephrology, University of Virginia, Lynchburg, USA.

Cureus
|September 16, 2021
PubMed

Insights

Candida parapsilosis can cause serious invasive fungal infections in peritoneal dialysis patients. Early diagnosis and treatment are crucial for managing this rare pathogen and preventing complications.

Area of Science:

  • Mycology
  • Nephrology
  • Infectious Diseases

Background:

  • Invasive fungal infections pose significant risks, particularly in immunocompromised individuals.
  • Peritoneal dialysis patients are susceptible to infections, including rare fungal pathogens.
  • Candida parapsilosis is an uncommon but potentially severe cause of invasive candidiasis.

Observation:

  • A 75-year-old female on home peritoneal dialysis presented with peritonitis.
  • Diagnostic workup revealed infection caused by Candida parapsilosis.
  • The patient had end-stage renal disease.

Findings:

  • The patient received a four-week course of oral fluconazole.
  • Following treatment, the patient was transitioned to in-center hemodialysis.
  • Successful management of Candida parapsilosis peritonitis was achieved.

Implications:

  • Physicians must maintain a high index of suspicion for Candida parapsilosis in peritoneal dialysis patients with peritonitis.
  • Prompt diagnosis and appropriate antifungal therapy are essential for favorable patient outcomes.
  • Awareness of this pathogen's potential in dialysis patients is critical for timely intervention.
Keywords:
candida parapsilosisend stage renal diseaseinvasive fungal infectionperitoneal dialysisperitonitis

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