Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

481
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
481
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

6.0K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
6.0K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

347
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
347
Cancer Therapies02:49

Cancer Therapies

8.3K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.3K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.4K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.4K
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

1.5K
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy of injectable platelet-rich fibrin and cross-linked hyaluronic acid for augmentation of interdental papilla in terms of true and surrogate end points.

Journal of Indian Society of Periodontology·2026
Same author

Comparative evaluation of tumor necrosis factor-α levels in gingival crevicular fluid, HbA1c levels, and homeostatic model assessment for insulin resistance in nondiabetic subjects with and without periodontitis.

Journal of Indian Society of Periodontology·2025
Same author

Collagen matrix versus free gingival graft for augmentation of keratinized tissue in mandibular anterior teeth: A comparative clinical study.

Journal of Indian Society of Periodontology·2025
Same author

Self-negligence and awareness among oral precancerous and cancer patients - A cross-sectional questionnaire study.

Journal of oral and maxillofacial pathology : JOMFP·2023
Same author

Aggressive giant cell lesion of mandible-confusing to common: true neoplasm versus reactive lesion.

BMJ case reports·2023
Same author

Burden of oral precancer and cancer among an indigenous tribal population of South India - An evaluative study.

Indian journal of dental research : official publication of Indian Society for Dental Research·2023

Related Experiment Video

Updated: Oct 20, 2025

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
08:55

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Published on: November 30, 2016

16.6K

Understanding Cachexia in Head and Neck Cancer.

Sivaramakrishnan Muthanandam1, Jananni Muthu2

  • 1Department of Oral and Maxillofacial Pathology and Oral Microbiology, Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth (Deemed to be) University, Puducherry, India.

Asia-Pacific Journal of Oncology Nursing
|September 16, 2021
PubMed
Summary

Cancer cachexia, a major cancer comorbidity, causes significant weight loss and fatigue. This review explores its impact on head and neck cancer patients, highlighting research gaps.

Keywords:
Cachexiacancerhead and neck canceroral cancer

More Related Videos

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
06:11

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

10.0K
Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
06:08

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Published on: June 2, 2023

2.0K

Related Experiment Videos

Last Updated: Oct 20, 2025

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
08:55

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Published on: November 30, 2016

16.6K
Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
06:11

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

10.0K
Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
06:08

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Published on: June 2, 2023

2.0K

Area of Science:

  • Oncology
  • Metabolic Syndrome
  • Nutrition Science

Background:

  • Cancer cachexia is a complex, multifactorial syndrome impacting cancer patients globally.
  • It is characterized by severe weight loss, anorexia, asthenia, and anemia.
  • Head and neck cancer (HNC) patients face heightened risks due to direct anatomical involvement affecting nutritional intake.

Purpose of the Study:

  • To review the concept of cancer cachexia specifically in the context of head and neck cancers.
  • To summarize current research findings on cachexia in HNC patients.
  • To identify gaps in the scientific understanding and management of HNC-related cachexia.

Main Methods:

  • Literature review of scientific evidence on cancer cachexia.
  • Focus on studies pertaining to head and neck cancer patient populations.
  • Synthesis of recent research findings and clinical observations.

Main Results:

  • Cancer cachexia presents unique challenges in HNC patients, exacerbating morbidity.
  • Nutritional intake is significantly compromised in HNC patients, increasing cachexia prevalence.
  • Current research and management strategies for HNC cachexia remain underdeveloped.

Conclusions:

  • Cancer cachexia is a critical issue in head and neck oncology requiring further investigation.
  • Understanding the specific mechanisms and clinical implications in HNC is essential.
  • Developing targeted approaches for prevention and treatment is a priority for improving patient outcomes.