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Cancer immunotherapy: Recent advances and challenges.
Ruby Dhar1, Ashikh Seethy2, Sunil Singh1
1Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Journal of Cancer Research and Therapeutics
|September 16, 2021
Summary
Cancer immunotherapy trains the body's immune system to fight cancer cells. This review summarizes recent advances in this promising cancer treatment, highlighting challenges and future directions.
Area of Science:
- Oncology
- Immunology
- Genetics
Background:
- Cancer immunotherapy, also known as biologic therapy or biotherapy, leverages the immune system to combat cancer cells.
- Genomic instability, resulting from errors in DNA replication, can lead to mutations that predispose individuals to cancer.
- Recent advancements have led to novel targeted therapies and a new class of treatments that harness the body's own defense mechanisms against cancer.
Purpose of the Study:
- To review recent progress in cancer immunotherapy.
- To discuss the mechanisms, applications, and challenges of current cancer immunotherapy strategies.
- To provide an overview of emerging developments in the field.
Main Methods:
- Literature review of recent advances in cancer immunotherapy.
- Analysis of different immunotherapy approaches, including antibody-based therapies and T-cell engineering.
- Discussion of the shortcomings and challenges associated with these treatments.
Main Results:
- Cancer immunotherapy has emerged as a widely accepted and effective approach to cancer treatment.
- Key strategies include using antibodies to target cancer cell proteins and enhancing the patient's T lymphocytes to attack cancer.
- Despite significant progress, challenges and limitations remain in the field.
Conclusions:
- Cancer immunotherapy represents a significant advancement in oncology, offering new hope for patients.
- Further research is needed to overcome existing challenges and optimize treatment efficacy.
- The field holds great promise for future cancer prevention and treatment strategies.
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