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Published on: May 25, 2022
Oral lesions associated with COVID-19: A systematic review
Virgínia Dias Uzêda-E-Silva1, Isabella Brandão de Sá, Jakeline Martins
1School of Dentistry, Centro Universitário UniRuy Wyden, Av. Luis Viana Filho, 3230, Paralela Salvador, BA, Brazil. virginiauzeda@yahoo.com.br.
Background:
Oral lesions has been reported in coronavirus disease 2019 (COVID-19). However, there are gaps about the occurrence. The aim of this study was to describe the clinical characteristics of oral lesions in patients with COVID-19.
Methods:
A systematic review was conducted in four electronic databases (PubMed, Lilacs, Cochrane and Google Scholar) with the search terms: "coronavírus", "COVID-19", "SARS-CoV-2", "novel coronavírus", "2019nCoV", "oral manifestation", "mucosal lesions", "oral lesions", "mucosa viral lesions" and "oral conditions". Articles were limited to those published between january and july 2020, and in English.
Results:
Initially, 182 articles were found, after reading the titles and abstracts a total of 24 records were included for full-text reading. Finally, 22 articles were included for data extraction and assessement. We identified and subsequently discussed clinical characteristics and differential diagnosis.
Conclusions:
The etiology of many oral mucosal lesions is intimately related to infectious, immunological, and psychosocial factors. Therefore, amid the SARS-CoV-2 pandemic in which many doubts about the disease still remain, caution is needed when evaluating patients and establishing correlations with other diseases that could be associated.
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