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Updated: Oct 20, 2025
Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
Published on: April 21, 2019
Evaluation of a fully automated and completely quantitative allergen-specific IgE and total IgE detection assay
Huimin Huang1, Zhifeng Huang1, Peiyan Zheng1
1Department of Allergy and Clinical Immunology, National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, 151 Yan Jiang Rd., Guangzhou (Canton), China. sunbaoqing@vip.163.com.
Abstract:
Based on the current urgent need for an in vitro quantitative detection system for allergens in most hospitals in China, we introduced a novel allergen-specific immunoglobulin E detection system that employs a solid phase enzyme-linked immunoassay and evaluated its clinical performance. The system uses a special reaction component (innovative patents) to reduce the reaction time to 12 min, achieving point-of-care testing for allergy management, which is impressive compared to the 3-18 h testing time for all other systems. In addition, the AILEX system has excellent consistency with the ImmunoCAP reference method system; therefore, we recommend the introduction of the AILEX system for clinical auxiliary diagnosis in medical units.
