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Published on: May 26, 2023
Safety of surgical tracheostomy under continued antithrombotic therapy: A retrospective cohort study
Takayuki Sugaya1, Rumi Ueha1,2, Taku Sato1
1Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine, the University of Tokyo, Tokyo, Japan.
Insights
Surgical tracheostomy (ST) can be safely performed with continued antithrombotic therapy (CAT), showing no increased risk of complications. However, surgeons must be cautious with ST under local anesthesia or for airway emergencies.
Area of Science:
- Otolaryngology
- Surgical Procedures
- Cardiology
Background:
- Surgical tracheostomy (ST) management guidelines exist, but performing ST under continued antithrombotic therapy (CAT) presents challenges.
- Investigating risk factors for ST complications is crucial, particularly concerning CAT application.
Purpose of the Study:
- To investigate the risk factors for complications after surgical tracheostomy (ST).
- To focus on the application of continued antithrombotic therapy (CAT) during ST.
Main Methods:
- Retrospective cohort study.
- Analysis of medical records from 2009 to 2020 at a single center.
- Inclusion of patients who underwent ST, with a focus on those on CAT.
Main Results:
- No statistically significant differences in bleeding, infection, or subcutaneous emphysema were observed between patients on CAT and antithrombotic-naïve patients.
- Patients on CAT showed longer activated partial thromboplastin time and higher prothrombin time-international normalized ratio.
- ST under local anesthesia and ST for airway emergencies were identified as significant risk factors for early postoperative complications.
Conclusions:
- Surgical tracheostomy (ST) can be safely performed under continued antithrombotic therapy (CAT) without an increased risk of postoperative complications.
- Surgeons should exercise increased caution for early complications in ST performed under local anesthesia without intubation or in cases of airway emergencies.
Objective:
Although various guidelines have been established for the management of antithrombotic therapy during surgical treatments, surgical tracheostomy (ST) under continued antithrombotic therapy (CAT) remains challenging. Here, we investigated the risk factors for complications after ST by focusing on the application of CAT during ST.
Design:
A retrospective cohort study with medical records from 2009 to 2020.
Setting:
A single-center study.
Participants:
This study included patients who had undergone ST at the Department of Otolaryngology of our hospital MAIN OUTCOME MEASURES: The primary outcomes were the incidence of complications and blood test results. Secondary outcomes were risk factors for postoperative complications.
Results:
We identified 288 patients (median age: 64 years; 184 men [64%]), among whom 40 (median age: 67 years; 29 men [73%]) underwent CAT. Although the patients undergoing CAT had significantly longer activated partial thromboplastin time (p=0.002) and a higher prothrombin time-international normalized ratio (p=0.006) compared to antithrombotic naïve patients, no statistically significant intergroup differences were observed for the risk of bleeding, infection, or subcutaneous emphysema. Instead, ST under local anesthesia (p=0.01) and ST for airway emergency (p=0.02) significantly increased the risk of early postoperative complications.
Conclusion:
These results suggest that ST under CAT can be safely performed without any increased risk of postoperative complications. Nevertheless, surgeons should be extra cautious about early complications after ST under local anesthesia without intubation or ST for airway emergencies.
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